Structure of PDB 8s0l Chain A

Receptor sequence
>8s0lA (length=369) Species: 9606 (Homo sapiens) [Search protein sequence]
GIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRK
SWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSA
GNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNIVGGESALPGAWPWQVS
LHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFY
GAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMM
LQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITP
AMICAGFLQGNVDSCQGDAGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPG
VYGNVMVFTDWIYRQMRAD
3D structure
PDB8s0l TMPRSS2 is a functional receptor for human coronavirus HKU1
ChainA
Resolution1.8 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A N131 D134 V136 H138 D144 E145 N15 D18 V20 H22 D28 E29
External links
PDB RCSB:8s0l, PDBe:8s0l, PDBj:8s0l
PDBsum8s0l
PubMed38964326
UniProtO15393|TMPS2_HUMAN Transmembrane protease serine 2 (Gene Name=TMPRSS2)

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