Structure of PDB 8rwk Chain A

Receptor sequence
>8rwkA (length=495) Species: 580239 (Saccharomyces cerevisiae SK1) [Search protein sequence]
SHLPMTVPIKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEIC
HIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKD
VIASIETLDNGKAISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHF
SYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSA
LYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGR
HIYQSAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVC
CAGSRVYVEESIYDKFIEEFKAASESIKVGDPFDESTFQGAQTSQMQLNK
ILKYVDIGKNEGATLITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFG
PVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVW
INTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAVRAKLDE
3D structure
PDB8rwk FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis.
ChainA
Resolution3.8 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A N192 E218 G248 G252 F266 S269 T272 C324 E421 N168 E194 G224 G228 F242 S245 T248 C300 E397
Gene Ontology
Molecular Function
GO:0004029 aldehyde dehydrogenase (NAD+) activity
GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006067 ethanol metabolic process
GO:0006090 pyruvate metabolic process
GO:0006740 NADPH regeneration
GO:0019413 acetate biosynthetic process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0042645 mitochondrial nucleoid

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rwk, PDBe:8rwk, PDBj:8rwk
PDBsum8rwk
PubMed38906101
UniProtP46367|ALDH4_YEAST Potassium-activated aldehyde dehydrogenase, mitochondrial (Gene Name=ALD4)

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