Structure of PDB 8rng Chain A

Receptor sequence

>8rngA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFHTSVSRPGRGEPRFISVGYVDGTQFVRFDSDAASPRTEPRAP
WIEQEGPEYWDRNTQISKTNTQTYRESLRNLRGYYNQSEAGSHTLQRMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGTCVEWLRRHLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP

3D structure

PDB

8rng Crystal structure of HLA B*18:01 in complex with TEVETYVL, an 8-mer epitope from Influenza A

Chain

Resolution

1.45 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	Y7 H9 S24 Y59 N63 I66 N70 T73 E76 S77 Y84 R97 Y99 Y123 T143 K146 W147 V152 Q155 Y159 W167	Y7 H9 S24 Y59 N63 I66 N70 T73 E76 S77 Y84 R97 Y99 Y123 T143 K146 W147 V152 Q155 Y159 W167
BS02	MG	A	T94 Q96 A117 Y118 D119 G120	T94 Q96 A117 Y118 D119 G120
BS03	MG	A	L78 R82 H93 Y118	L78 R82 H93 Y118
BS04	MG	A	S13 R14 G18 E19 P20	S13 R14 G18 E19 P20

External links

PDB	RCSB:8rng, PDBe:8rng, PDBj:8rng
PDBsum	8rng
PubMed
UniProt	S6AU73

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