Structure of PDB 8rhq Chain A

Receptor sequence
>8rhqA (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSVSRPEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIE
QEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGCDV
GPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHAA
EQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRC
WALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGE
EQRYTCHVQHEGLPKPLTLRWEL
3D structure
PDB8rhq The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 Y9 E63 N66 Q70 T73 D74 D77 T80 I95 I97 Y99 R114 D116 T143 K146 W147 A152 Q155 Y159 R163 W167 Y171 Y7 Y9 E60 N63 Q67 T70 D71 D74 T77 I92 I94 Y96 R111 D113 T140 K143 W144 A149 Q152 Y156 R160 W164 Y168
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:8rhq, PDBe:8rhq, PDBj:8rhq
PDBsum8rhq
PubMed38742159
UniProtQ5S3G3

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