Structure of PDB 8rhi Chain A

Receptor sequence
>8rhiA (length=276) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
HHHSSGENLYFQGIWDRMRDGFQLQDAISTNPRIERQRLWFLSNQSFLEQ
SSARGSLYMHYVVERLEERNMPLELALLPVIESAYNPFALSRSNAAGLWQ
FIPATGQHFNLRQTNFYDGRRDITASTNAALTYLERLHDMFNGDWMLALA
AYNAGEGTVSRAIERNEKLGLPTDYWNLPLPQETQDYVPKLLALSQIVMA
PDSYGISLNPINNEPYFQAVRVKRGIDLSSVAALANLDEDELYQLNPAYK
RRVTMDGPQQLLVPMEKAAFLTASLD
3D structure
PDB8rhi Structural characterization of lytic transglycosylase MltD of Pseudomonas aeruginosa, a target for the natural product bulgecin A.
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BLG A E144 S153 R154 S155 Q162 F163 I164 T167 Y195 Y214 N215 A216 G217 E245 E82 S91 R92 S93 Q100 F101 I102 T105 Y133 Y152 N153 A154 G155 E183
BS02 ZN A E197 D201 E135 D139
BS03 ZN A H63 H65 H1 H3
BS04 ZN A H64 D82 H2 D20
BS05 ZN A E226 E229 E164 E167
Gene Ontology
Molecular Function
GO:0008933 lytic transglycosylase activity
Biological Process
GO:0000270 peptidoglycan metabolic process
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:8rhi, PDBe:8rhi, PDBj:8rhi
PDBsum8rhi
PubMed38583835
UniProtQ9I2T2

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