Structure of PDB 8rhf Chain A

Receptor sequence
>8rhfA (length=327) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
HHHHHHSSGENLYFQGIWDRMRDGFQLQDAISTNPRIERQRLWFLSNQSF
LEQSSARGSLYMHYVVERLEERNMPLELALLPVIESAYNPFALSRSNAAG
LWQFIPATGQHFNLRQTNFYDGRRDITASTNAALTYLERLHDMFNGDWML
ALAAYNAGEGTVSRAIERNEKLGLPTDYWNLPLPQETQDYVPKLLALSQI
VMAPDSYGISLNPINNEPYFQAVRVKRGIDLSSVAALANLDEDELYQLNP
AYKRRVTMDGPQQLLVPMEKAAFLTASLDTTAWQQYRVRSGDSLHSIANR
YRITVAELKSANRLSNHLRKGQQLSIP
3D structure
PDB8rhf Structural characterization of lytic transglycosylase MltD of Pseudomonas aeruginosa, a target for the natural product bulgecin A.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BLG A E144 S153 R154 S155 Q162 F163 I164 T167 Y195 Y214 N215 A216 G217 E245 E85 S94 R95 S96 Q103 F104 I105 T108 Y136 Y155 N156 A157 G158 E186
BS02 ZN A E197 D201 E138 D142
BS03 ZN A H61 H64 H2 H5
BS04 ZN A H63 H65 E69 D82 H4 H6 E10 D23
Gene Ontology
Molecular Function
GO:0008933 lytic transglycosylase activity
Biological Process
GO:0000270 peptidoglycan metabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rhf, PDBe:8rhf, PDBj:8rhf
PDBsum8rhf
PubMed38583835
UniProtQ9I2T2

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