Structure of PDB 8rh7 Chain A

Receptor sequence

>8rh7A (length=322) Species: 9606 (Homo sapiens) [Search protein sequence]

DFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLS
FPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDG
KVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGN
DSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFF
LLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNAS
MPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQDTHAIDK
YSRIIFPAAYILFNLIYWSIFS

3D structure

PDB

8rh7 Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor

Chain

Resolution

2.78 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	EST	A	N332 S339	N248 S255

External links

PDB	RCSB:8rh7, PDBe:8rh7, PDBj:8rh7
PDBsum	8rh7
PubMed
UniProt	P24046\|GBRR1_HUMAN Gamma-aminobutyric acid receptor subunit rho-1 (Gene Name=GABRR1)

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