Structure of PDB 8rh4 Chain A

Receptor sequence
>8rh4A (length=332) Species: 9606 (Homo sapiens) [Search protein sequence]
SEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYL
RHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTD
NVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTED
DLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYIN
FTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTM
STIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQER
KEQDTHAIDKYSRIIFPAAYILFNLIYWSIFS
3D structure
PDB8rh4 Divergent mechanisms of steroid inhibition in the human rho1 GABAA receptor
ChainA
Resolution2.52 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EST A S334 P336 S260 P262
BS02 EST A N332 R337 N258 R263
External links
PDB RCSB:8rh4, PDBe:8rh4, PDBj:8rh4
PDBsum8rh4
PubMed
UniProtP24046|GBRR1_HUMAN Gamma-aminobutyric acid receptor subunit rho-1 (Gene Name=GABRR1)

[Back to BioLiP]