Structure of PDB 8rcw Chain A

Receptor sequence
>8rcwA (length=205) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
GSLIRATNLWGYTDLMRELGADPLPFLRRFDIPPGIEHQEDAFMSLAGFV
RMLEASAAELDCPDFGLRLARWQGLGILGPVAVIARNAATLFGGLEAIGR
YLYVHSPALTLTVSSTTARSNVRFGYEVTEPGIPYPLQGYELSMANAARM
IRLLGGPQARARVFSFRHAQLGTDAAYREALGCTVRFGRTWCGFEVDHRL
AGRPI
3D structure
PDB8rcw Crystal structure of the Mycobacterium tuberculosis VirS regulator reveals its interaction with the lead compound SMARt751.
ChainA
Resolution1.692 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YQF A N11 I101 L114 Y129 G142 S146 N149 M153 F197 N8 I98 L111 Y126 G139 S143 N146 M150 F194
External links
PDB RCSB:8rcw, PDBe:8rcw, PDBj:8rcw
PDBsum8rcw
PubMed38548139
UniProtP9WMJ3|VIRS_MYCTU HTH-type transcriptional regulator VirS (Gene Name=virS)

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