Structure of PDB 8rcb Chain A

Receptor sequence

>8rcbA (length=957) Species: 882 (Nitratidesulfovibrio vulgaris str. Hildenborough)

ELQKLQWAKQTTSICCYCAVGCGLIVHTAKDGQGRAVNVEGDPDHPINEG
SLCPKGASIFQLGENDQRGTQPLYRAPFSDTWKPVTWDFALTEIAKRIKK
TRDASFTEKNAAGDLVNRTEAIASFGSAAMDNEECWAYGNILRSLGLVYI
EHQARICHSPTVPALAESFGRGAMTNHWNDLANSDCILIMGSNAAENHPI
AFKWVLRAKDKGATLIHVDPRFTRTSARCDVYAPIRSGADIPFLGGLIKY
ILDNKLYFTDYVREYTNASLIVGEKFSFKDGLFSGYDAANKKYDKSMWAF
ELDANGVPKRDPALKHPRCVINLLKKHYERYNLDKVAAITGTSKEQLQQV
YKAYAATGKPDKAGTIMYAMGWTHSVGVQNIRAMAMIQLLLGNIGVAGGG
VNALRGESNVQGSTDQGLLAHIWPGYNPVPNSKAATLELYNAATPQSKDP
MSVNWWQNRPKYVASYLKALYPDEEPAAAYDYLPRIDAGRKLTDYFWLNI
FEKMDKGEFKGLFAWGMNPACGGANANKNRKAMGKLEWLVNVNLFENETS
SFWKGPGMNPAEIGTEVFFLPCCVSIEKEGSVANSGRWMQWRYRGPKPYA
ETKPDGDIMLDMFKKVRELYAKEGGAYPAPIAKLNIADWEEHNEFSPTKV
AKLMNGYFLKDTEVGGKQFKKGQQVPSFAFLTADGSTCSGNWLHAGSFTD
AGNLMARRDKTQTPEQARIGLFPNWSFCWPVNRRILYNRASVDKTGKPWN
PAKAVIEWKDGKWVGDVVDGGGDPGTKHPFIMQTHGFGALYGPGREEGPF
PEHYEPLECPVSKNPFSKQLHNPVAAVCDPRYPFIGTTYRVTEHWQTGLM
TRRCAWLVEAEPQIFCEISKELAKLRGIGNGDTVKVSSLRGALEAVAIVT
ERIRPFKIEGVDVHMVGLPWHYGWMVPKNGGDTANLLTPSAGIPETKAFM
VDVRKVW

3D structure

• PDB: 8rcb Substrate-dependent oxidative inactivation of a W-dependent formate dehydrogenase involving selenocysteine displacement
• Chain: A
• Resolution: 2.11 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MGD	A	K90 G226 S227 N228 N232 D254 P255 R256 S272 D275 A404 M405 G406 W407 G442 Y883 R884 T886 H888 W889 Q890 K996	K55 G191 S192 N193 N197 D219 P220 R221 S237 D240 A369 M370 G371 W372 G406 Y839 R840 T842 H844 W845 Q846 K947
BS02	MGD	A	A164 Q188 M405 E443 G552 M553 N554 N579 C608 K614 D641 T882 R884 Q890 T891 L893 M894 W964 N979 T995	A129 Q153 M370 E407 G516 M517 N518 N543 C572 K578 D605 T838 R840 Q846 T847 L849 M850 W920 N935 T946
BS03	SF4	A	C50 C53 C57 L87 C88 K90 P234 I235	C15 C18 C22 L52 C53 K55 P199 I200
BS04	OXY	A	I191 U192	I156 U157

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0030151 molybdenum ion binding
• GO:0046872 metal ion binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0009061 anaerobic respiration

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:8rcb, PDBe:8rcb, PDBj:8rcb
• PDBsum: 8rcb
• PubMed: 39148770
• UniProt: Q72EJ1