Structure of PDB 8rbu Chain A

Receptor sequence
>8rbuA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB8rbu The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 Y9 E63 N66 V67 A69 Q70 T73 D74 D77 T80 I95 Y99 D116 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167 Y171 Y7 Y9 E63 N66 V67 A69 Q70 T73 D74 D77 T80 I95 Y99 D116 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167 Y171
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:8rbu, PDBe:8rbu, PDBj:8rbu
PDBsum8rbu
PubMed38742159
UniProtQ5S3G3

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