Structure of PDB 8r6b Chain A

Receptor sequence
>8r6bA (length=165) Species: 9606 (Homo sapiens) [Search protein sequence]
GNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSVVLGQVDAQL
VPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWT
AYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRL
RRRLDLAYPLTVGSI
3D structure
PDB8r6b A ligand discovery toolbox for the WWE domain family of human E3 ligases
ChainA
Resolution2.5 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP A W111 Y121 Y149 Q158 N160 T163 R165 R167 W92 Y102 Y130 Q139 N141 T144 R146 R148
External links
PDB RCSB:8r6b, PDBe:8r6b, PDBj:8r6b
PDBsum8r6b
PubMed39048679
UniProtQ86Y01|DTX1_HUMAN E3 ubiquitin-protein ligase DTX1 (Gene Name=DTX1)

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