Structure of PDB 8r3f Chain A

Receptor sequence
>8r3fA (length=103) Species: 9606 (Homo sapiens) [Search protein sequence]
ELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEME
ATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTY
HPV
3D structure
PDB8r3f Ligandability assessment of the C-terminal Rel-homology domain of NFAT1.
ChainA
Resolution1.55 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 XS8 A F603 T604 S605 K630 S633 Q634 P635 F28 T29 S30 K55 S58 Q59 P60
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8r3f, PDBe:8r3f, PDBj:8r3f
PDBsum8r3f
PubMed38396281
UniProtQ13469|NFAC2_HUMAN Nuclear factor of activated T-cells, cytoplasmic 2 (Gene Name=NFATC2)

[Back to BioLiP]