Structure of PDB 8r2g Chain A

Receptor sequence
>8r2gA (length=239) Species: 9606 (Homo sapiens) [Search protein sequence]
GFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKT
QLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDA
VLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDF
SGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTPIGGHILAHAST
TRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGD
3D structure
PDB8r2g Crystal structure of a BRCA2-DMC1 complex
ChainA
Resolution3.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q144 P146 P152 G153 G154 N178 Q61 P63 P69 G70 G71 N95
Gene Ontology
Molecular Function
GO:0000150 DNA strand exchange activity
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0007131 reciprocal meiotic recombination
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8r2g, PDBe:8r2g, PDBj:8r2g
PDBsum8r2g
PubMed
UniProtQ14565|DMC1_HUMAN Meiotic recombination protein DMC1/LIM15 homolog (Gene Name=DMC1)

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