Structure of PDB 8qzx Chain A

Receptor sequence
>8qzxA (length=333) Species: 5722 (Trichomonas vaginalis) [Search protein sequence]
TTPLVKGYVPDDNGKFDFDKMLEQMKYCGFQATNLGLAIDQINEMLHYDY
EPKLFGLGGGVEGVKYKPRACKIFLGITSNLISSGMRDYIRFLVKHALVD
VVVCTAGGIEEDFIKCLAPTHMGEFFHDGHDLRKRGLNRILIVPNKNYCL
FEDWIMPILDKCLEEQNTQGTKWTPSKLIHRLGLEINNEDSVWYWAAKNN
IPVYSPALTDGSIGDMIYFHSYNNPGLVLDLVEDIRDMNNEPLWATKTGC
IILGGGVVKHHIMNANLYRNGADFVVYVNTAHDFDGSDSGARPDEAVSWG
AISLEAKPVKVYAEVTLVLPLLVAGSFSKFLAE
3D structure
PDB8qzx Structural characterization of the (deoxy)hypusination in Trichomonas vaginalis questions the bifunctionality of deoxyhypusine synthase.
ChainA
Resolution3.01 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A T106 S107 N108 T133 D240 G285 N309 T310 E344 V345 T78 S79 N80 T105 D210 G255 N279 T280 E314 V315
BS02 NAD A H290 D315 S317 D318 S319 H260 D285 S287 D288 S289
Gene Ontology
Molecular Function
GO:0034038 deoxyhypusine synthase activity
Biological Process
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qzx, PDBe:8qzx, PDBj:8qzx
PDBsum8qzx
PubMed38923395
UniProtF1AQF9

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