Structure of PDB 8qwm Chain A

Receptor sequence
>8qwmA (length=196) Species: 9606 (Homo sapiens) [Search protein sequence]
SVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKLFCQLAKTCPVQL
WVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLI
RVEGNLRVECLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCYSSCMGG
MNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENLRK
3D structure
PDB8qwm Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators.
ChainA
Resolution1.54 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C176 H179 C238 C242 C81 H84 C143 C147
External links
PDB RCSB:8qwm, PDBe:8qwm, PDBj:8qwm
PDBsum8qwm
PubMed38862470
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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