Structure of PDB 8qwk Chain A

Receptor sequence
>8qwkA (length=186) Species: 9606 (Homo sapiens) [Search protein sequence]
SVPSQKTYQGSYGFRLGFLVTCTCSPALNKLFCQLAKTCPVQLWVDSTPP
PGTRVRAMAIYKQSQHMTEVVRRCPHHERCDGLAPPQHLIRVEGNLRAEY
LDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCYSSCMGGMNRRPILTII
TLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENLRK
3D structure
PDB8qwk Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators.
ChainA
Resolution1.69 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C176 H179 C242 C74 H77 C137
External links
PDB RCSB:8qwk, PDBe:8qwk, PDBj:8qwk
PDBsum8qwk
PubMed38862470
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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