Structure of PDB 8qpl Chain A

Receptor sequence
>8qplA (length=331) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
MKFGIEFVPNEPIQKLCYYVKLAEDNGFEYCWITDHYNNRNVYMALTAIA
MNTNKIKLGPGVTNPYVRSPAITASAIATLDELSGGRAVLGIGPGDKATF
DALGIEWVKPVTTLKESIEVIRKLLAGERVSYEGKVVKIAGAALAVKPIQ
KAVPVYMGAQGPKMLETAGMIADGVLINASNPKDFEAAIPLIKKGAEAAG
RSMDEIDVAAYACMSVDKNADKAKQAAVPVVAFIAAGSPPVVLERHGIDM
EKVEAIRNALKSGNFPEAFKNVDDTMLEAFSIYGTPEDVVEKCKKLAEMG
VTQIVAGSPIGPNKETAIKLIGKKVIPALKE
3D structure
PDB8qpl Mutational and structural studies of ( beta alpha ) 8 -barrel fold methylene-tetrahydropterin reductases utilizing a common catalytic mechanism.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.5.98.2: 5,10-methylenetetrahydromethanopterin reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F42 A T34 D35 H36 G61 V62 P94 G95 W107 K109 P110 V111 T112 Q160 G161 P162 K163 M164 Y211 T34 D35 H36 G61 V62 P94 G95 W107 K109 P110 V111 T112 Q160 G161 P162 K163 M164 Y211
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0018537 coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity
Biological Process
GO:0006730 one-carbon metabolic process
GO:0015948 methanogenesis
GO:0019386 methanogenesis, from carbon dioxide
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:8qpl, PDBe:8qpl, PDBj:8qpl
PDBsum8qpl
PubMed38747406
UniProtQ58929|MER_METJA 5,10-methylenetetrahydromethanopterin reductase (Gene Name=mer)

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