Structure of PDB 8qnn Chain A

Receptor sequence
>8qnnA (length=259) Species: 135487 (Nocardia cyriacigeorgica) [Search protein sequence]
ADPRFAALETTAGARLGVFAVNTGSERTVAHRADERFPMASTFKGLACGA
LLREHPLSTGYFDQVIHYSAEELVDYSPVTETRVESGMTVAELCHAAITA
SDNTAGNQLLKLLGGPQGFTAFLRSLGDDTSRLDRWETELNTAIPGDERD
TTTPAALAADYRALVVGDVLGEPERAQLTAWLVANTTGDTRIRAGLPEDW
TVGDKTGSPAYGSALDVAVTWPSGRAPIVIAVLSTKSEQDAEPDNRLVAD
ATRTVVDVL
3D structure
PDB8qnn Biochemical and structural characterization of a class A beta-lactamase from Nocardia cyriacigeorgica.
ChainA
Resolution1.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FLC A S114 S174 T279 G280 S281 S41 S101 T206 G207 S208
BS02 FLC A H168 W254 H95 W181
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
Biological Process
GO:0017001 antibiotic catabolic process
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8qnn, PDBe:8qnn, PDBj:8qnn
PDBsum8qnn
PubMed38168018
UniProtA0A5R8NCK8

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