Structure of PDB 8qnc Chain A

Receptor sequence

>8qncA (length=486) Species: 32630 (synthetic construct)

DEHTITNWSGTHAVRPKRFFQPESVEELEKIVKEAHEKGQKIRPVGSGLS
PNGLAFSEDGMVSLALMDKVLHVDKEKKQVTVQAGARVQQVVDALRPHGL
TLQNFGSISEQQIGGFIQVGAHGTGARIPPVDEQVVSMKLVTPAKGTIEL
SEEKDPELFRLARCGLGALGVVTEVTLQCVPRHKLLEHTFVATMKEVKKN
HEKLLRENKHVRYMWIPYTDTVVVVTCNPLPEGKKAPKVKPQYSEDEKLQ
PLRNLLREAAPETSPEVSGLSFTELRDALLAVDPLDTEWVKRVNQAEAEF
WKRSEGYRVGWSDEILGFDCGGQQWVSEVAFPAGTLEKPSAADLEYMEEL
MRLINKEGIPAPAPIEQRWTAGSSSPMSPAYSPSPDSVFSWVGIIMYLPT
EDEEQRKAITEAFRQYRKLCETRLWDKYGAAEHWAKIEVPEDPEELEALR
ERLRKRYPGVDKFNKARRELDPKNILSNDMIDSLFP

3D structure

• PDB: 8qnc Crystal structure of ancestral L-galactono-1,4-lactone dehydrogenase: A113G variant
• Chain: A
• Resolution: 1.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	W15 R50 P51 V52 G53 S54 G55 L56 S57 L61 A62 G113 S114 I115 Q118 G122 Q125 V126 A128 H129 L173 G174 V178 V179 R388 H453 A455	W8 R43 P44 V45 G46 S47 G48 L49 S50 L54 A55 G106 S107 I108 Q111 G115 Q118 V119 A121 H122 L166 G167 V171 V172 R368 H433 A435

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Mon Dec 2 23:16:07 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '8qnc', asym_id = 'A', title = 'Crystal structure of ancestral L-galactono-1,4-lactone dehydrogenase: A113G variant'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='8qnc', asym_id='A', title='Crystal structure of ancestral L-galactono-1,4-lactone dehydrogenase: A113G variant')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0003885,0016020,0016633,0016899,0050660,0071949', uniprot = '', pdbid = '8qnc', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003885,0016020,0016633,0016899,0050660,0071949', uniprot='', pdbid='8qnc', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>