Structure of PDB 8qn0 Chain A

Receptor sequence
>8qn0A (length=322) Species: 9606 (Homo sapiens) [Search protein sequence]
APLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWR
YQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLG
LSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESI
KANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEA
GGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW
ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHW
TQMDKPTEVNQILIKWLDSDAR
3D structure
PDB8qn0 Photosensitization enables Pauson-Khand-type reactions with nitrenes.
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.76: lipid-phosphate phosphatase.
3.3.2.10: soluble epoxide hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WJ5 A D335 W336 Y383 M419 Y466 V498 L499 H524 D110 W111 Y158 M194 Y241 V273 L274 H299
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:8qn0, PDBe:8qn0, PDBj:8qn0
PDBsum8qn0
PubMed38301027
UniProtP34913|HYES_HUMAN Bifunctional epoxide hydrolase 2 (Gene Name=EPHX2)

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