Structure of PDB 8qmf Chain A

Receptor sequence
>8qmfA (length=678) Species: 196600 (Vibrio vulnificus YJ016) [Search protein sequence]
MDRKHLANAIRALSMDGVQKANSGHPGAPMGMADIAEVLWRGHLNHNPSN
PEWADRDRFVLSNGHGSMLIYSLLHLSGYELSIDDLKNFRQLHSKTPGHP
EYGYAPGIETTTGPLGQGITNAVGMAMAEKALAAQFNKEGHDIVDHFTYV
FMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDT
PKRFEAYGWHVIPAVDGHNAEAINAAIEAAKADPRPTLICTKTIIGFGSP
NKSGSHDCHGAPLGAEEIAATRKELGWEHGPFEIPQEVYAEWSAKEAGAA
KEAAWNEKFAAYEAAYPELAAEFKRRVNGELPAQWEEKANQIIADLQANP
ANIASRKASQNALEAFGKMLPEFMGGSADLAPSNLTMWSGSKSLEASDFS
GNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALM
KVQNIQVYTHDSIGLGEDGPTHQPVEQIASLRLTPNMSTWRPCDQVESAV
AWKLAIERKDGPSALIFSRQNLAQQERTAEQVADIAKGGYILKDSDGKPE
LILIATGSEVELAVKAAEQLTAEGKKVRVVSMPATDAFDKQDAAYRESVL
PSDVTARIAIEAGITDFWYKYVGFDGRIIGMTTFGESAPADQLFEMFGFT
VENVVNTAKELLAENLYFQGLEHHHHHH
3D structure
PDB8qmf Structural determination and kinetic analysis of the Transketolase from Vibrio vulnificus reveal unexpected cooperative behavior.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.2.1.1: transketolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TPP A H65 G113 L115 D154 G155 N184 I186 I188 I245 H259 H65 G113 L115 D154 G155 N184 I186 I188 I245 H259
BS02 MG A D154 N184 I186 D154 N184 I186
BS03 TPP A D379 E410 F436 Y439 D379 E410 F436 Y439
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004802 transketolase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006098 pentose-phosphate shunt
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qmf, PDBe:8qmf, PDBj:8qmf
PDBsum8qmf
PubMed38145310
UniProtQ7MDD4|TKT2_VIBVY Transketolase 2 (Gene Name=tkt2)

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