Structure of PDB 8qki Chain A

Receptor sequence
>8qkiA (length=207) Species: 9606 (Homo sapiens) [Search protein sequence]
MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSS
FICNTLQPGCNSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQH
IEKKMLRLRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMV
RLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLI
IRACARR
3D structure
PDB8qki Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
ChainA
Resolution3.46 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR A L9 L10 L25 F29 S85 A88 L9 L10 L25 F29 S85 A88
BS02 CLR A W3 I30 W3 I30
External links
PDB RCSB:8qki, PDBe:8qki, PDBj:8qki
PDBsum8qki
PubMed
UniProtP08034|CXB1_HUMAN Gap junction beta-1 protein (Gene Name=GJB1)

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