Structure of PDB 8qjf Chain A

Receptor sequence

>8qjfA (length=196) Species: 9606 (Homo sapiens) [Search protein sequence]

MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSS
FICNTLQPGCNSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQH
IEKKMISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVY
PCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRAC

3D structure

PDB

8qjf Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate

Chain

Resolution

2.86 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CLR	A	L9 S85	L9 S85
BS02	CLR	A	M1 W3 L6	M1 W3 L6

External links

PDB	RCSB:8qjf, PDBe:8qjf, PDBj:8qjf
PDBsum	8qjf
PubMed
UniProt	P08034\|CXB1_HUMAN Gap junction beta-1 protein (Gene Name=GJB1)

[Back to BioLiP]