Structure of PDB 8qh8 Chain A

Receptor sequence
>8qh8A (length=258) Species: 9606 (Homo sapiens) [Search protein sequence]
HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYD
QATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDG
QGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSA
KPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPL
LECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKN
RQIKASFK
3D structure
PDB8qh8 Human Carbonic Anhydrase II in complex with Lasamide (2,4-Dichloro 5-sulfamoyl benzoic acid)
ChainA
Resolution1.04 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A H94 H96 H119 H92 H94 H117
BS02 V8I A Q92 H94 H119 L198 T199 T200 Q90 H92 H117 L195 T196 T197
External links
PDB RCSB:8qh8, PDBe:8qh8, PDBj:8qh8
PDBsum8qh8
PubMed
UniProtP00918|CAH2_HUMAN Carbonic anhydrase 2 (Gene Name=CA2)

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