Structure of PDB 8qh4 Chain A

Receptor sequence
>8qh4A (length=156) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence]
EFEFPEELKTKLQEHINYFPKKRQAILLCLHEIQNYYGYIPPESLKPLAD
MLELPLNHVEGVVAFYDMFDREDKAKYRIRVCVSIVCHLMGTNKLLKALE
NILGIKPGEVTPDGKFKIVPVQCLGACSEAPVFMVNDDEYKFESEVQLNE
ILSRYT
3D structure
PDB8qh4 Structures of 3-acetylpyridine adenine dinucleotide and ADP-ribose bound to the electron input module of respiratory complex I.
ChainA
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FES A C86 V90 C91 C127 L128 A130 C131 C82 V86 C87 C123 L124 A126 C127
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0051537 2 iron, 2 sulfur cluster binding
Cellular Component
GO:0045271 respiratory chain complex I

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8qh4, PDBe:8qh4, PDBj:8qh4
PDBsum8qh4
PubMed38503292
UniProtO66842|NUOE_AQUAE NADH-quinone oxidoreductase subunit E (Gene Name=nuoE)

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