Structure of PDB 8qer Chain A

Receptor sequence
>8qerA (length=413) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SMSRRRVVITGMGMLSPLGLDVPSSWEGILAGRSGIAPIEHMDLSAYSTR
FGGSVKGFNVEEYLSAKEARKLDLFIQYGLAASFQAVRDSGLEVTDANRE
RIGVSMGSGIGGLTNIENNCRSLFEQGPRRISPFFVPGSIINMVSGFLSI
HLGLQGPNYALTTAATTGTHSIGMAARNIAYGEADVMVAGGSEMAACGLG
LGGFGAARALSTRNDEPTRASRPWDRDRDGFVLSDGSGALVLEELEHARA
RGARIYAELVGFGMSGDAFHMTAPPEDGAGAARCMKNALRDAGLDPRQVD
YINAHGTSTPAGDIAEIAAVKSVFGEHAHALSMSSTKSMTGHLLGAAGAV
EAIFSVLALRDQVAPPTINLDNPDEGCDLDLVAHEAKPRKIDVALSNSFG
FGGTNGTLVFRRF
3D structure
PDB8qer New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.179: beta-ketoacyl-[acyl-carrier-protein] synthase II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UGL A T271 P273 H304 G311 A314 F398 G399 F400 T272 P274 H305 G312 A315 F399 G400 F401
Gene Ontology
Molecular Function
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
Biological Process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qer, PDBe:8qer, PDBj:8qer
PDBsum8qer
PubMed
UniProtG3XDA2

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