Structure of PDB 8qe8 Chain A

Receptor sequence
>8qe8A (length=373) Species: 9606 (Homo sapiens) [Search protein sequence]
QSDEDVIRLIGQHLNGTVDLLMQEPPRRLQTLLRQAVELQRDRCLYHNTK
LDNNLDSVSLLIDHVCSRRQFPCYTQQILTEHCNEVWFCKFSNDGTKLAT
GSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPD
DCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQ
CDLDGNLLDSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTDRNI
VQEDHPIMSFTISKNGRLALLNVATQGVHLWDLQDRVLVRKYQGVTQGFY
TIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWN
PQIPSMMASASDDGTVRIWGPAP
3D structure
PDB8qe8 Non-canonical substrate targeting by the supramolecular CTLH E3 ligase reveals an WDR26-YPEL5 regulatory module
ChainA
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C300 H303 H320 C322 C44 H47 H64 C66
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0034657 GID complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qe8, PDBe:8qe8, PDBj:8qe8
PDBsum8qe8
PubMed38759627
UniProtQ9H7D7|WDR26_HUMAN WD repeat-containing protein 26 (Gene Name=WDR26)

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