Structure of PDB 8q44 Chain A

Receptor sequence
>8q44A (length=435) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence]
MNEKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDY
AKKLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTG
GTKTMVVHIYNFLKEKFKKIKFEGSYLDARDYKLVYDYSEEAISLKDTIK
IDINTLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKGE
DFVKWLEDPFRKIFKGENKLLEKTAKFKKHIEKLLKDNDSSPIVKFNEKT
PQFIWDILNAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKW
FEWYVYSQIKSELLDRKLKEGEHFGISLKAQKKDSPYFELDIFLINGYQL
IGISLTTSSTRRLCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQ
KDLAYETGSTQKRFVVFGIDDWADIGSKICEEVFK
3D structure
PDB8q44 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R213 N299 K301 T358 T359 S360 R211 N297 K299 T356 T357 S358
BS02 rna A G11 T12 N13 P16 S36 T47 T99 G101 T102 K103 Y128 A131 R132 E384 T409 G410 G11 T12 N13 P16 S36 T47 T99 G101 T102 K103 Y126 A129 R130 E382 T407 G408
BS03 MN A D343 L357 D341 L355
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q44, PDBe:8q44, PDBj:8q44
PDBsum8q44
PubMed38033326
UniProtE8URK0

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