Structure of PDB 8q42 Chain A

Receptor sequence
>8q42A (length=434) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence]
NEKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDYA
KKLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTGG
TKTMVVHIYNFLKEKFKNNKIKFEGSYLDARDYKLVYDYSEEAISLKDTI
KIDINTLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKG
EDFVKWLEDPFRKIFKGENKLLEKTAKFKKHIEKLLKDSSPIVKFNEKTP
QFIWDILNAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKWF
EWYVYSQIKSELLDRKLKEGEHFGISLKAQKKDSPYFALDIFLINGYQLI
GISLTTSSTRELCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQK
DLAYETGSTQKRFVVFGIDDWADIGSKICEEVFK
3D structure
PDB8q42 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
ChainA
Resolution1.97 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R213 N299 G300 K301 T358 T359 S360 R212 N296 G297 K298 T355 T356 S357
BS02 rna A G11 T12 N13 P16 S36 T47 T99 G101 T102 K103 Y128 A131 R132 E384 T409 G410 G10 T11 N12 P15 S35 T46 T98 G100 T101 K102 Y127 A130 R131 E381 T406 G407
BS03 MN A D343 L357 D340 L354
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q42, PDBe:8q42, PDBj:8q42
PDBsum8q42
PubMed38033326
UniProtE8URK0

[Back to BioLiP]