Structure of PDB 8q2q Chain A

Receptor sequence
>8q2qA (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB8q2q Crystal structure of YTHDC1 in complex with Compound 2b (YL_32)
ChainA
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IT6 A K361 S362 N363 N364 N367 W377 S378 W428 D476 K18 S19 N20 N21 N24 W34 S35 W85 D133
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:8q2q, PDBe:8q2q, PDBj:8q2q
PDBsum8q2q
PubMed38787793
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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