Structure of PDB 8q1z Chain A

Receptor sequence
>8q1zA (length=311) Species: 9606 (Homo sapiens) [Search protein sequence]
FPEGKVLDDMEGNQWVLGKKIGLIYLAFPTNKPEKDARHVVKVEYQENGP
LFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFM
VMERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKA
ANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSL
DAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLD
ELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKILNPHGIP
LGPLDFSTKGQ
3D structure
PDB8q1z Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-296
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IKD A I43 V59 E122 L124 D127 A170 L173 I24 V40 E103 L105 D108 A151 L154
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8q1z, PDBe:8q1z, PDBj:8q1z
PDBsum8q1z
PubMed
UniProtQ86Y07|VRK2_HUMAN Serine/threonine-protein kinase VRK2 (Gene Name=VRK2)

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