Structure of PDB 8q1k Chain A

Receptor sequence
>8q1kA (length=420) Species: 9606 (Homo sapiens) [Search protein sequence]
QRPAPCYDPCEAVLVESIPEGLDFPNAGNPSTSQAWLGLLAGAHSSLDIA
SFYWTLTNNDTHTQEPSAQQGEEVLRQLQTLAPKGVNVRIAVSKPSGPQP
QADLQALLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSANMDWRS
LTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYDTRY
NQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNVVDNARSFIY
VAVMNYLPTLEFSHPHRFWPAIDDGLRRATYERGVKVRLLISCWGHSEPS
MRAFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTE
RATYIGTSNWSGNYFTETAGTSLLVTQNGRGGLRSQLEAIFLRDWDSPYS
HDLDTSADSVGNACRLLAAQ
3D structure
PDB8q1k Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
ChainA
Resolution1.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.16.1: spleen exonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A A295 L308 F438 A222 L235 F365
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:8q1k, PDBe:8q1k, PDBj:8q1k
PDBsum8q1k
PubMed37994783
UniProtQ8IV08|PLD3_HUMAN 5'-3' exonuclease PLD3 (Gene Name=PLD3)

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