Structure of PDB 8pzp Chain A

Receptor sequence
>8pzpA (length=470) Species: 382835 (Influenza A virus (A/WSN/1933(H1N1))) [Search protein sequence]
NATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSA
FDERRNKYLEEHPSAGKDPKKTGGPIYRRVDGKWRRELILYDKEEIRRIW
RQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGS
TLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYE
RMCNILKGKFQTAAQRTMVDQVRESRNPGNAEFEDLIFLARSALILRGSV
AHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNE
NPAHKSQLVWMACHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNEN
METMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTFSVQRNLPF
DRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEK
ATSPIVPSFDMSNEGSYFFG
3D structure
PDB8pzp Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation.
ChainA
Resolution8.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A V299 T390 R391 S392 Q398 R461 V279 T370 R371 S372 Q378 R441
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075732 viral penetration into host nucleus
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8pzp, PDBe:8pzp, PDBj:8pzp
PDBsum8pzp
PubMed38100595
UniProtA0A2Z5UJ33

[Back to BioLiP]