Structure of PDB 8px2 Chain A

Receptor sequence
>8px2A (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
MGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKH
PMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKL
QDVFEFRYAKMPD
3D structure
PDB8px2 Structure Guided Design of a Domain Selective Bromodomain and Extra Terminal (BET) N-Terminal Bromodomain Chemical Probe
ChainA
Resolution1.622 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NUB A W370 P371 F372 L381 Y428 N429 H433 W28 P29 F30 L39 Y86 N87 H91
External links
PDB RCSB:8px2, PDBe:8px2, PDBj:8px2
PDBsum8px2
PubMed37967462
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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