Structure of PDB 8psx Chain A

Receptor sequence

>8psxA (length=417) Species: 1549864 (Tilapia lake virus) [Search protein sequence]

MDSRFAQLTGVFCDDFTYSEGSRRFLSSYSTVERRPGVPVEGDCYDCLKN
KWIAFELEGQPRKFPKATVRCILNNDATYVCSEQEYQQICKVQFKDYLEI
DGVVKVGHKASYDAELRERLLELPHPKSGPKPRIEWVAPPRLADISKETA
ELKRQYGFFECSKFLACGEECGLDQEARELILNEYARDREFEFRNGGWIQ
RYTVASHKPATQKILPLPASAPLARELLMLIARSTTQAGKVLHSDNTSIL
AVPVMRDSGKHSKRRPTASTHHLVVGLSKPGCEHDFEFDGYRAAVHVMHL
DPKQSANIGEQDFVSTREIYKLDMLELPPISRKGDLDRASGLETRWDVIL
LLECLDSTRVSQAVAQHFNRHRLALSVCKDEFRKGYQLASEIRGTIPLSS
LYYSLCAVRLRMTVHPF

3D structure

PDB

8psx Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.

Chain

Resolution

2.96 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	Y202 A205 H207 K208 V254 M255 K263 S269 T270 H271 H299 L300 Q304 L355 S357 R393 G394 P397	Y202 A205 H207 K208 V254 M255 K263 S269 T270 H271 H299 L300 Q304 L355 S357 R393 G394 P397
BS02	ZN	A	C161 C282 H284 H296	C161 C282 H284 H296

External links

PDB	RCSB:8psx, PDBe:8psx, PDBj:8psx
PDBsum	8psx
PubMed	38066000
UniProt	A0A142I7Z3

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