Structure of PDB 8pr7 Chain A

Receptor sequence
>8pr7A (length=253) Species: 9606 (Homo sapiens) [Search protein sequence]
KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG
VEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQ
KLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIA
NFLAGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEAATYAE
TYKRISRVEFAFPAFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITAN
SSK
3D structure
PDB8pr7 Aurora-A in complex with CEP192 and an inhibitory monobody
ChainA
Resolution2.76 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A G140 A160 K162 A213 G17 A37 K39 A90
External links
PDB RCSB:8pr7, PDBe:8pr7, PDBj:8pr7
PDBsum8pr7
PubMed
UniProtO14965|AURKA_HUMAN Aurora kinase A (Gene Name=AURKA)

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