Structure of PDB 8pq5 Chain A

Receptor sequence

>8pq5A (length=353) Species: 9606 (Homo sapiens) [Search protein sequence]

GFLKLIEIENFKSYKGRQIIGPFQRFTAIIGPNGSGKSNLMDAISFVLGE
KTSNLRVKTLRDLIHGAPVGKPAANRAFVSMVYSEEGAEDRTFARVIVGG
SSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKER
TALFEEISRSGELAQEYDKRKKEMVKAEEDAKKAKQAFEQIKKERFDRFN
ACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKR
FRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDQIDAALDNTNIGKVA
NYIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCVISKVLTFDLT
KYP

3D structure

PDB

8pq5 Conformational dynamics of the human Cohesin ATPase module

Chain

Resolution

4.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ATP	A	K13 S14 N34 G35 S36 G37 K38 S39 N40 R57 P69 Q137	K12 S13 N33 G34 S35 G36 K37 S38 N39 R56 P68 Q136
BS02	ATP	A	R1123 S1129 G1131 E1132 D1163	R252 S258 G260 E261 D292

External links

PDB	RCSB:8pq5, PDBe:8pq5, PDBj:8pq5
PDBsum	8pq5
PubMed

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