Structure of PDB 8pos Chain A

Receptor sequence
>8posA (length=168) Species: 292805 (Wolbachia endosymbiont strain TRS of Brugia malayi) [Search protein sequence]
SEGVTIEFKIVGLNKKLKVFTTCPHTLFGASFCAVAIEHPIVQDLMSKEI
QDLISSQGKNNEKVGIYTGLNVKHPFLDKELPLYVANFVLMEYREGAIFG
CPAHDQRDFEFAQEYDLPIIPVISSAIEEYTNNSIMFNSEFLNGLTVSEA
RKVIVEKLEEKGIGKKTI
3D structure
PDB8pos Targeting A Microbiota Wolbachian Aminoacyl-tRNA Synthetase To Block Its Pathogenic Host
ChainA
Resolution2.137 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.4: leucine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7RZ A S221 T241 T242 C243 T246 L313 Y316 I321 F322 D328 D331 S1 T21 T22 C23 T26 L90 Y93 I98 F99 D105 D108
External links
PDB RCSB:8pos, PDBe:8pos, PDBj:8pos
PDBsum8pos
PubMed38985862
UniProtQ5GS31|SYL_WOLTR Leucine--tRNA ligase (Gene Name=leuS)

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