Structure of PDB 8po8 Chain A

Receptor sequence
>8po8A (length=603) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
QQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQAIFQEMAKE
IDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETG
SGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGC
IGYKVRFSNHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERS
LNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRT
YPVEVRYRPIVEEADDTERDQLQAIFDAVDELSQESPGDILIFMSGEREI
RDTADALNKLNLRHTEILPLYARLSNSEQNRVFQSHSGRRIVLATNVAET
SLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRV
SEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPF
VEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLA
RMVLEAQKHGCVREAMIITSALSIQDPRESDFLAFVNLWNYLGEQQKALS
SNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIH
IAL
3D structure
PDB8po8 Structural insights into the N-terminal APHB domain of HrpA: mediating canonical and i-motif recognition.
ChainA
Resolution2.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R26 R29 R30 V34 A42 I46 D478 K485 R23 R26 R27 V31 A39 I43 D475 K482
BS02 dna A R22 R26 R19 R23
BS03 ADP A T102 G103 G105 K106 T107 T108 R141 F336 T356 T99 G100 G102 K103 T104 T105 R138 F333 T353
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:8po8, PDBe:8po8, PDBj:8po8
PDBsum8po8
PubMed38412313
UniProtP43329|HRPA_ECOLI ATP-dependent RNA helicase HrpA (Gene Name=hrpA)

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