Structure of PDB 8pmk Chain A

Receptor sequence

>8pmkA (length=502) Species: 96773 (Thauera chlorobenzoica)

AERVGEKDLRAALEWFRSKGYLVETNKEVNPDLEITGLQKIFDGSLPMLF
NNVKDMPHARAITNLFGDIRVVEELFGWENSLDRVKKVARAIDHPLKPVI
IGQDEAPVQEEVLTTDLDVNKWLTAIRHTPLETEMTIGSGISCVVGPYFD
GGSHIGYNRMNFRWGNVGTFQISPGSHMWQVMTEHYKDDEPIPLTMCFGV
PPSCTYVAGAGFDYAILPKGCDEIGIAGAIQGSPVRLVKCRTIDAYTLAD
AEYVLEGYLHPRDKRYETAESEAADIQGRFHFHPEWAGYMGKAYKAPTFH
VTAITMRRRESKPIIFPLGVHTADDANIDTSVRESAIFALCERLQPGIVQ
NVHIPYCMTDWGGCIIQVKKRNQIEEGWQRNFLAAILACSQGMRLAIAVS
EDVDIYSMDDIMWCLTTRVNPQTDILNPLPGGRGQTFMPSNTQFEGGMGI
DATVPYGYESDFHRPVYGVDLVKPENFFDAKDIDKMKSRMAGWVLSLART
GR

3D structure

• PDB: 8pmk Active Pcd complex with prFMN bound
• Chain: A
• Resolution: 2.43 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BYN	A	G150 H166 Y169 N170 R171 Q183 S185 H189 A220 G221 A222 G223 Y226 H295 L330 D337 D341 W373	G138 H154 Y157 N158 R159 Q171 S173 H177 A208 G209 A210 G211 Y214 H283 L318 D325 D329 W361
BS02	FE	A	H166 H189 E235	H154 H177 E223
BS03	FE	A	R430 D436 D476 A477 T478	R418 D424 D451 A452 T453
BS04	FE	A	T342 E346 I366	T330 E334 I354

Gene Ontology

Molecular Function

• GO:0016831 carboxy-lyase activity

Biological Process

• GO:0033494 ferulate metabolic process
• GO:0046281 cinnamic acid catabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:8pmk, PDBe:8pmk, PDBj:8pmk
• PDBsum: 8pmk
• UniProt: A0A193DUB4