Structure of PDB 8pkb Chain A

Receptor sequence
>8pkbA (length=296) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
MLLGSHVSMSGKKMLEGSAIEAHEYGETTFMIYTGAPQNTRRKSIEDLNI
TKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQA
IGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKG
TEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEF
DKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSF
KDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQHFDPELKNKVMQQ
3D structure
PDB8pkb Octahedrally coordinated iron in the catalytic site of endonuclease IV from Staphylococcus aureus
ChainA
Resolution1.9 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FE A H68 H109 E144 H68 H109 E144
BS02 FE A E144 D178 H213 E258 E144 D178 H213 E258
BS03 ZN A H181 D226 H228 H181 D226 H228
Gene Ontology
Molecular Function
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519 endonuclease activity
GO:0008081 phosphoric diester hydrolase activity
GO:0008270 zinc ion binding
GO:0008833 deoxyribonuclease IV (phage-T4-induced) activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function

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Biological Process
External links
PDB RCSB:8pkb, PDBe:8pkb, PDBj:8pkb
PDBsum8pkb
PubMed
UniProtQ6GGE2|END4_STAAR Probable endonuclease 4 (Gene Name=nfo)

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