Structure of PDB 8pk6 Chain A

Receptor sequence
>8pk6A (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
LEMKIFSESHKTVFVVDHCPYMAESSLWTCSVESSMEYCRIMYDIFPFKK
LVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILH
GLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSHVRM
LEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGLVSDRSKKELS
PVLTSEVHSVRAGRHLATKLNILVQQHFD
3D structure
PDB8pk6 Basis of gene-specific transcription regulation by the Integrator complex.
ChainA
Resolution3.21 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S101 L103 V107 E111 S150 H151 M154 C158 E161 E165 K168 S97 L99 V103 E107 S146 H147 M150 C154 E157 E161 K164
External links
PDB RCSB:8pk6, PDBe:8pk6, PDBj:8pk6
PDBsum8pk6
PubMed38906142
UniProtQ9NVM9|INT13_HUMAN Integrator complex subunit 13 (Gene Name=INTS13)

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