Structure of PDB 8pk1 Chain A

Receptor sequence
>8pk1A (length=107) Species: 1268061 (Streptococcus thermophilus DGCC 7710) [Search protein sequence]
YMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNHTA
NTAMVGRLKANNPKKGNITILTVTEKQFARMIYLYGDKNTSIANSEERLV
FLGDNYC
3D structure
PDB8pk1 Structural basis for spacer acquisition in a type II-A CRISPR-Cas system
ChainA
Resolution3.17 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R26 K30 R22 K26
BS02 dna A F12 D13 P15 T16 Y25 R29 F42 S43 Y45 F8 D9 P11 T12 Y21 R25 F38 S39 Y41
BS03 dna A H52 K80 H48 K76
BS04 MG A F12 D13 S43 F8 D9 S39
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8pk1, PDBe:8pk1, PDBj:8pk1
PDBsum8pk1
PubMed
UniProtG3ECR3|CAS2_STRTR CRISPR-associated endoribonuclease Cas2 (Gene Name=cas2)

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