Structure of PDB 8pi0 Chain A

Receptor sequence

>8pi0A (length=168) Species: 9606 (Homo sapiens) [Search protein sequence]

MTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGET
CLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQI
KRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQ
GVDDAFYTLVREIRKHKE

3D structure

PDB

8pi0 NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 5-(1H-indol-2-l)piperazin-2-one

Chain

Resolution

N/A

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	YVW	A	K5 L6 V7 E37 D38 S39 D54 L56 T74	K5 L6 V7 E37 D38 S39 D54 L56 T74

External links

PDB	RCSB:8pi0, PDBe:8pi0, PDBj:8pi0
PDBsum	8pi0
PubMed
UniProt	P01116\|RASK_HUMAN GTPase KRas (Gene Name=KRAS)

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