Structure of PDB 8phe Chain A

Receptor sequence
>8pheA (length=551) Species: 9606 (Homo sapiens) [Search protein sequence]
AFAKELFLGKIKKKEVFPFPEVSQDELNEINQFLGPVEKFFTEEVDSRKI
DQEGKIPDETLEKLKSLGLFGLQVPEEYGGLGFSNTMYSRLGEIISMDGS
ITVTLAAHQAIGLKGIILAGTEEQKAKYLPKLASGEHIAAFCLTEPASGS
DAASIRSRATLSEDKKHYILNGSKVWITNGGLANIFTVFAKTEVVDSDGS
VKDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCEVHFENTKIPVENILG
EVGDGFKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQFNKRLS
EFGLIQEKFALMAQKAYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSS
EAAWQCVSEALQILGGLGYTRDYPYERILRDTRILLIFEGTNEILRMYIA
LTGLQHAGRILTTRIHHGVVHPSLADSANKFEENTYCFGRTVETLLLRFG
KTIMEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANT
FCVEAYLQNLFSLSQLDKYAPENLDEQIKKVSQQILEKRAYICAHPLDRT
C
3D structure
PDB8phe The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.8.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F332 N333 F295 N296
BS02 peptide A L180 D188 A190 S191 I192 K239 I242 F293 M297 I431 Y435 L438 Q442 K521 M524 L143 D151 A153 S154 I155 K202 I205 F256 M260 I394 Y398 L401 Q405 K451 M454
Gene Ontology
Molecular Function
GO:0003995 acyl-CoA dehydrogenase activity
GO:0004466 long-chain fatty acyl-CoA dehydrogenase activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
GO:0070991 medium-chain fatty acyl-CoA dehydrogenase activity
Biological Process
GO:0001676 long-chain fatty acid metabolic process
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0051791 medium-chain fatty acid metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0030425 dendrite
GO:0031966 mitochondrial membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8phe, PDBe:8phe, PDBj:8phe
PDBsum8phe
PubMed38086790
UniProtQ9H845|ACAD9_HUMAN Complex I assembly factor ACAD9, mitochondrial (Gene Name=ACAD9)

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