Structure of PDB 8pe2 Chain A

Receptor sequence
>8pe2A (length=443) Species: 746128 (Aspergillus fumigatus) [Search protein sequence]
TLPVIEAKGNKFFYSNNGTEFFIRGVAYQQEYNSDYTDPLANVDNCKRDI
PYLKQLRTNVIRTYAVDPTKDHDECMKLLDDAGIYLITDLSAPSESINRA
DPAWNTDLYKRYTSVIDAFAKYSNVIGFFAGNEVANDNNNTNSIAYVKAA
VRDMKSYIKSKDYRSSLLVGYATDDDAHIRADLADYLVCGDKESSIDMFG
YNIYEWCGDSSFEKSGYKDRTEEFSKYPVPAFFSEYGCIDPKPRKFTDVA
ALYGPQMNDVWSGGIVYMYFQEANDYGLVSVSGDNVKTKEDFSYLSVQMQ
KVTATGVNSASYTASNTAVPTCPSVGAKWEASNKLPPSPNSELCDCMVET
LSCTVKDSVDEKEYGDLFDYLCAAGVCGGINSNSTSGDYGAYSVCSAKQK
LSFVMNQYYKKNNKAATACDFDGKAQTKKGADASGSCASLISQ
3D structure
PDB8pe2 Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases.
ChainA
Resolution2.05 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A Q81 S322 Q55 S296
BS02 MAN A S319 Y320 S293 Y294
BS03 MAN A T347 C348 S350 T321 C322 S324
External links
PDB RCSB:8pe2, PDBe:8pe2, PDBj:8pe2
PDBsum8pe2
PubMed38856634
UniProtP0C956|GEL4_ASPFU 1,3-beta-glucanosyltransferase gel4 (Gene Name=gel4)

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