Structure of PDB 8pdv Chain A

Receptor sequence
>8pdvA (length=1027) Species: 7668 (Strongylocentrotus purpuratus) [Search protein sequence]
AHAPKVIVFISGSCLFGAISRSLFKKLPIPYTVVLLILGAILGVVASNVP
LVEEHTRDVAHMDPHVLLQIFLPVLIFESAFAMDVHTFMRSFSQVCILAL
FGLVVASVLTAVLAMNLFNYNWNFSEAMMFGAIMSATDPVAVVALLKDLG
ASKQLGTIIEGESLLNDGCAIVIFNVFMKMVFFPQLTSTVGQNVLYFLQV
AVAGPLWGYAVAKVTVFFLSHIFNDALVEITITLAATYLTYYIGDIWLEV
SGVLAVVVLGLIVNAEKTSISPEVEVFLHRFWEMLAYLANTLIFMMVGVV
VTQKALVAVDKMDWFYLIILYLAITIIRGMVISLFSPILSRIGYGLTWRN
AVIMTWGGLRGAVGLALALVVENLAGNDVIGSKFLFHTAGIVVLTLVINA
TTIQTLLRILGMSDISIPKRLAMAGAVRRIHEGQNRTLNMLKSDRFLADA
DWDIATAACEISDPYSPSPREFADMMEEARLRMLKAEKISYWKQFEHGML
AREALRLLVQHAEVAADEKDQFILVDDLKKSWQIKGIYPWLKRKLEDLIS
EKKIAKLMYKICHHMAFEVTINIAIVLNIVPIIMEFVVQDKMALQKIEDA
LRISNYVFFVIYAIEAIVKILGLGRHYIVSHWNKFDAFILVVALVDIIII
KVVKLFRLLRGLRMLRLTKALIPKLILVVNGKINNQLSLGYDVGKGYIIG
EEEVGKIIDRMVDNKKILRELKHISETGRLQVVKELGLLQREHPGIAVSV
KTRQAIRTILNHSRETIHELQGAGLLDEMEAHKLELTVEIKMKRLMNAPS
SIPPPPPENLLKNVSWLAGDMKLIDFIKARASLLHFDYGEVIVREGDESD
GLFLIVSGLVKLYGKVFEDYLTVGNVIGEMGVLTKKPRNATVTCETTVQV
YFITAEDMNIAIDTFTLYPSLEYRLWRVVAIRIATPLIMEQMAFQGWTQE
KVKLHLERGYLVDLAESHFQFNIDATLEDVILINGTAYNAHTREEIRSPC
LISRTVHKLTFQYTATEEPRLFVVRNA
3D structure
PDB8pdv Structures of a sperm-specific solute carrier gated by voltage and cAMP.
ChainA
Resolution3.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PCG A F1032 I1042 G1043 E1044 M1045 R1053 N1054 R1097 F867 I877 G878 E879 M880 R888 N889 R932
Gene Ontology
Molecular Function
GO:0015297 antiporter activity
GO:0015385 sodium:proton antiporter activity
Biological Process
GO:0006812 monoatomic cation transport
GO:0055085 transmembrane transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8pdv, PDBe:8pdv, PDBj:8pdv
PDBsum8pdv
PubMed37880361
UniProtA3RL54|SL9C1_STRPU Sperm-specific sodium:proton exchanger (Gene Name=SLC9C1)

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