Structure of PDB 8pdr Chain A

Receptor sequence
>8pdrA (length=351) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence]
DLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEILYAKHADY
KYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSLGKIKNNKGE
DLQMLDIHGVEKSWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPI
ILLCVGALIFTKLASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARS
FYDLFEQKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTML
RWGVIARSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPK
AGLLSLANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLK
E
3D structure
PDB8pdr Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
ChainA
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y53 I103 R132 K133 M135 R151 S153 Y44 I94 R123 K124 M126 R142 S144
BS02 rna A K171 A173 S174 R185 R186 R189 G255 T257 W261 S314 I334 M337 Y338 R339 K162 A164 S165 R176 R177 R180 G246 T248 W252 S305 I325 M328 Y329 R330
BS03 rna A V190 L243 N246 V181 L234 N237
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

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Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8pdr, PDBe:8pdr, PDBj:8pdr
PDBsum8pdr
PubMed37993464
UniProtQ6WBA1|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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