Structure of PDB 8pdp Chain A

Receptor sequence
>8pdpA (length=363) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence]
MSLQGIHLSDLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGE
ILYAKHADYKYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSL
GKIKNNKGEDLQMLDIHGVEKSWVEEIDKEARKTMATLLKESSIPQNQRP
SAPDTPIILLCVGALIFTKLASTIEVGLETTVRRANRVLSDALKRYPRMD
IPKIARSFYDLFEQKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQAY
GAGQTMLRWGVIARSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESGLL
HLRQSPKAGLLSLANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSAAE
SYAKSLKESNKIN
3D structure
PDB8pdp Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A E50 I103 R132 K133 M135 R151 S153 E50 I103 R132 K133 M135 R149 S151
BS02 rna A K171 A173 S174 R185 R186 R189 G255 T257 W261 S314 Y338 R339 K169 A171 S172 R183 R184 R187 G253 T255 W259 S312 Y336 R337
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8pdp, PDBe:8pdp, PDBj:8pdp
PDBsum8pdp
PubMed37993464
UniProtQ6WBA1|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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